时间:2019-01-13 作者:英语课 分类:VOA标准英语2012年(一月)


英语课

Scientists Identify Deafness Gene 1 in Mice


 


Scientists have identified a gene that causes deafness in mice, and they say it could lead to a better understanding of hereditary 2 deafness in humans and maybe new treatments in the future.



Scientists had previously 3 focused on a group of genes 4 that were associated with inherited deafness, but now researchers at Washington University in Saint Louis have implicated 5 a specific gene.



"So, when we inactivated 6 the FGF20 gene in mice, we find that the resulting mice had no ability to hear, although they were otherwise very healthy, they were fertile, and they lived a normal lifespan," says senior researcher David Ornitz, adding work by other scientists pointed 7 them to that particular gene.



When examined, the mice had visible changes in their inner ear. Outer hair cells - critical to hearing - normally run in a densely 8 packed row, but in these mice the hair cells were patchy, and there were fewer of them.



"So we found there is patchy formation of sensory 9 cells," says post-doctoral fellow Sung-Ho Huh. "And we also found, within the sensory cells, we found the number of specific outer hair cells had decreased, but the inner hair cells are intact."









Researchers at Washington University in Saint Louis have identified a specific gene that causes deafness in mice.




Hereditary deafness is relatively 10 rare. Much more common is hearing loss that comes with age or exposure to noise. Right now, about the only treatment is hearing aids. But Ornitz says a better understanding of how the FGF20 gene is linked to the body's system for capturing sound could lead to new therapies.



"Eventually, it might be possible to use a gene therapy approach or some other drug-type approach, in which you could actually correct a deficit 11 due to loss or inactivation 12 of FGF20. But that will require quite a bit more research."



n.遗传因子,基因
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
adj.遗传的,遗传性的,可继承的,世袭的
  • The Queen of England is a hereditary ruler.英国女王是世袭的统治者。
  • In men,hair loss is hereditary.男性脱发属于遗传。
adv.以前,先前(地)
  • The bicycle tyre blew out at a previously damaged point.自行车胎在以前损坏过的地方又爆开了。
  • Let me digress for a moment and explain what had happened previously.让我岔开一会儿,解释原先发生了什么。
n.基因( gene的名词复数 )
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
adj.密切关联的;牵涉其中的
  • These groups are very strongly implicated in the violence. 这些组织与这起暴力事件有着极大的关联。 来自《简明英汉词典》
  • Having the stolen goods in his possession implicated him in the robbery. 因藏有赃物使他涉有偷盗的嫌疑。 来自《现代汉英综合大词典》
v.使不活泼,阻止活动( inactivate的过去式和过去分词 )
  • Molluscicides are quickly inactivated by sunlight and adsorption to mud organic matter. 灭螺剂因阳光作用、泥土及有机物质的吸收会很快失效。 来自辞典例句
  • Viruses were inactivated by BPL and the toxicity measured again. BPL对病毒进行灭活,测定残存毒力。 来自互联网
adj.尖的,直截了当的
  • He gave me a very sharp pointed pencil.他给我一支削得非常尖的铅笔。
  • She wished to show Mrs.John Dashwood by this pointed invitation to her brother.她想通过对达茨伍德夫人提出直截了当的邀请向她的哥哥表示出来。
ad.密集地;浓厚地
  • A grove of trees shadowed the house densely. 树丛把这幢房子遮蔽得很密实。
  • We passed through miles of densely wooded country. 我们穿过好几英里茂密的林地。
adj.知觉的,感觉的,知觉器官的
  • Human powers of sensory discrimination are limited.人类感官分辨能力有限。
  • The sensory system may undergo long-term adaptation in alien environments.感觉系统对陌生的环境可能经过长时期才能适应。
adv.比较...地,相对地
  • The rabbit is a relatively recent introduction in Australia.兔子是相对较新引入澳大利亚的物种。
  • The operation was relatively painless.手术相对来说不痛。
n.亏空,亏损;赤字,逆差
  • The directors have reported a deficit of 2.5 million dollars.董事们报告赤字为250万美元。
  • We have a great deficit this year.我们今年有很大亏损。
n.灭活,失活,钝化(作用);减化
  • This inactivation may be accomplished in a variety of ways. 这种失去活性作用能以多种方式来实现。 来自辞典例句
  • Long sonication periods can lead to some inactivation. 长时间的声波作用可导致某种程度的失活。 来自辞典例句
学英语单词
acid-test ratio
ahigh
arc suppressing coil
as crooked as a dog's hind leg
asswhore
automatic stabilizer
avoiding chord
azzones
ballsbridge
Bergatreute
biocapacity
bleached paddy soil
buckling criteria
Cimanuk, Sungai
closed grating
coefficient of utilization of useful capacity
colloidal fuel
colpeurynter introducing forceps
commodity producer
conductive band
convolation
cordons sanitaires
cross sell
dessicator
dicky-seat
Dmitrovsk-Orlovskiy
dominant laterality
double squirrelcage motor
ecological system
elevator apron
epimera
erysipelas gangraenosum
eschewal
Football's a game of two halves
forfending
formula plan
froben
genus limnobiums
glucoscilliphaeoside
Hall's anchor
hip line
homer a. thompsons
hydraulic-machinery
ignition-switch
input-output interface system
instantaneous center/centre of rotation
intrumental
isothymol
keyboard input
klepto
liver coccidiosis
log well
maritime law institute
mass-energy
mincer and bowl cutter
mode of transducer
Montils
multiethnic education
no-claim
nonresponses
one-hundred-dollar
passive infrared rangefinder
pedaling
permissible limit of vibration
personal contact
phospholipidomics
Photinia chingiana
phylum chaetognathas
Piggott
pinnatifid
posumbu
prosperoes
pseudotriton ruber
pyramid method of hull construction
pyrenophora japonica ito et kuribayashi
Ranella
reaming bit
rhyacophila formosana
ringal
screen house
searls
Semple treatment
sexidentate ligand
Sheykino
silicon impregnation
Soltvadkert
spermatorrheas
subspectra
syndesm-
Thal Des.
thixotropic hardening
thorup
three-membered
twin tail
two-track recorder
vacuum-gauge
Vallen
very low frequency band radiated field system
Vila da Maganja
vision signal
Wairio
wind measuring device