时间:2019-01-13 作者:英语课 分类:VOA标准英语2012年(一月)


英语课

Scientists Identify Deafness Gene 1 in Mice


 


Scientists have identified a gene that causes deafness in mice, and they say it could lead to a better understanding of hereditary 2 deafness in humans and maybe new treatments in the future.



Scientists had previously 3 focused on a group of genes 4 that were associated with inherited deafness, but now researchers at Washington University in Saint Louis have implicated 5 a specific gene.



"So, when we inactivated 6 the FGF20 gene in mice, we find that the resulting mice had no ability to hear, although they were otherwise very healthy, they were fertile, and they lived a normal lifespan," says senior researcher David Ornitz, adding work by other scientists pointed 7 them to that particular gene.



When examined, the mice had visible changes in their inner ear. Outer hair cells - critical to hearing - normally run in a densely 8 packed row, but in these mice the hair cells were patchy, and there were fewer of them.



"So we found there is patchy formation of sensory 9 cells," says post-doctoral fellow Sung-Ho Huh. "And we also found, within the sensory cells, we found the number of specific outer hair cells had decreased, but the inner hair cells are intact."









Researchers at Washington University in Saint Louis have identified a specific gene that causes deafness in mice.




Hereditary deafness is relatively 10 rare. Much more common is hearing loss that comes with age or exposure to noise. Right now, about the only treatment is hearing aids. But Ornitz says a better understanding of how the FGF20 gene is linked to the body's system for capturing sound could lead to new therapies.



"Eventually, it might be possible to use a gene therapy approach or some other drug-type approach, in which you could actually correct a deficit 11 due to loss or inactivation 12 of FGF20. But that will require quite a bit more research."



n.遗传因子,基因
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
adj.遗传的,遗传性的,可继承的,世袭的
  • The Queen of England is a hereditary ruler.英国女王是世袭的统治者。
  • In men,hair loss is hereditary.男性脱发属于遗传。
adv.以前,先前(地)
  • The bicycle tyre blew out at a previously damaged point.自行车胎在以前损坏过的地方又爆开了。
  • Let me digress for a moment and explain what had happened previously.让我岔开一会儿,解释原先发生了什么。
n.基因( gene的名词复数 )
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
adj.密切关联的;牵涉其中的
  • These groups are very strongly implicated in the violence. 这些组织与这起暴力事件有着极大的关联。 来自《简明英汉词典》
  • Having the stolen goods in his possession implicated him in the robbery. 因藏有赃物使他涉有偷盗的嫌疑。 来自《现代汉英综合大词典》
v.使不活泼,阻止活动( inactivate的过去式和过去分词 )
  • Molluscicides are quickly inactivated by sunlight and adsorption to mud organic matter. 灭螺剂因阳光作用、泥土及有机物质的吸收会很快失效。 来自辞典例句
  • Viruses were inactivated by BPL and the toxicity measured again. BPL对病毒进行灭活,测定残存毒力。 来自互联网
adj.尖的,直截了当的
  • He gave me a very sharp pointed pencil.他给我一支削得非常尖的铅笔。
  • She wished to show Mrs.John Dashwood by this pointed invitation to her brother.她想通过对达茨伍德夫人提出直截了当的邀请向她的哥哥表示出来。
ad.密集地;浓厚地
  • A grove of trees shadowed the house densely. 树丛把这幢房子遮蔽得很密实。
  • We passed through miles of densely wooded country. 我们穿过好几英里茂密的林地。
adj.知觉的,感觉的,知觉器官的
  • Human powers of sensory discrimination are limited.人类感官分辨能力有限。
  • The sensory system may undergo long-term adaptation in alien environments.感觉系统对陌生的环境可能经过长时期才能适应。
adv.比较...地,相对地
  • The rabbit is a relatively recent introduction in Australia.兔子是相对较新引入澳大利亚的物种。
  • The operation was relatively painless.手术相对来说不痛。
n.亏空,亏损;赤字,逆差
  • The directors have reported a deficit of 2.5 million dollars.董事们报告赤字为250万美元。
  • We have a great deficit this year.我们今年有很大亏损。
n.灭活,失活,钝化(作用);减化
  • This inactivation may be accomplished in a variety of ways. 这种失去活性作用能以多种方式来实现。 来自辞典例句
  • Long sonication periods can lead to some inactivation. 长时间的声波作用可导致某种程度的失活。 来自辞典例句
学英语单词
AAP (analyst assistance program)
air operating electric light
airbrushed
albizzin
amberized
antiartillery
autobike
balancing procedure
basal cell carcinoma of face
bearing holder
Bogatyrëvo
boot-leg
British Accounting Association
Brocard point
bucephala islandicas
Camellia parafurfuracea
carbon circuit breaker
centrifugal tar extractor
cinnabar moths
computer literacies
creepage distance
cushioned-seat coach
Darcy law of resistance
denomination currency
diddlysquats
discretionary wiring machine
double break contact
ductile fracture
dynamic balance test
e and m leads
ectopocystis
esophageal sarcoma
feareth
filsting
for-loop block
French type machinist's hammer
full-point
fuselis
hexachaetous
high frequency feeder
home monitoring
honeybush
impracticalities
intrinsicates
jeans' radiation law
kerb-crawlers
Kopites
Kārvāndar, Rūdkhāneh-ye
liability to outsiders
Lumsum
made mountains of molehills
magnetic isoanomalous line
malakoplakia of genitourinary system
male - pattern baldness
Mboula
microdosimetricspectra
microfilariae
Mitsuze-tōge
nasty-looking
non-contact magnetic recording
non-hazardous area
nonsister chromatids
officery
on all sides
opercular fold
perseverances
Piliophen
piquant sauce
Plexus venosus vesicalis
postdiction
precision thermometer
Puccinia scleriae
pulsus aequalis
radio frequency energy
rag-and-bone
reductios
retractable bit
reviviscible
rigger brush
ringing generator
sambas
SearchMash
sequential testing
single-phase three wire system
skandas
solar spectrum
songvid
spatial disequilibrium
squarenesses
stared out
Tar River
td.
think ... up
transabled
translation operation
tubularian
u-shaped adapter
upthrust bearing
vitamin K-1
VSIP
wall gecko
water-rot