VOA标准英语2010年-Genes Predict Who Will Live to Age 100
时间：2019-02-03 作者：英语课 分类：VOA标准英语2010年(七)月
Researchers at Boston University have identified a kind of genetic 2 signature in people who are likely to live to age 100 or older. The technique may also help doctors predict whether you're likely to get a disease, decades before the symptoms show up.
Living a long, healthy life tends to run in families. If your grandparents and parents lived into their 90s and remained relatively 3 healthy until the end, there's a pretty good chance you will, too.
So it's pretty clear genetics plays some role in longevity 4.
In this study, the research team developed a new statistical 5 way of analyzing 6 the genetic code of people who had reached age 100 as compared with people who had a more typical lifespan. Tom Perls, who heads the New England Centenarian Study, explains what they found.
"We discovered 150 or so genetic markers that can highly predict whether or not a person has the genetic propensity 7 to live to extreme old age."
Using just that large number of genetic markers, the team was able to predict in almost four out of five cases whether a person would live to be 100.
Perls says the key to successfully predicting long life was the sophisticated statistical analysis of many different gene 1 variations that each played some role.
"And that's what this method does - it captures the complexity 8 of the puzzle and the interaction of all these genes 9 together to produce exceptional longevity."
Perls and his colleagues publish their study in the online edition of the journal Science.
The Boston University researcher says this kind of analysis could play a role, not just in predicting who will live longest, but in actually helping 10 people live longer and healthier lives.
In an interview via Skype, Tom Perls said the same technique used to predict long life may also be used to predict whether a person might eventually develop certain diseases. He gave the example of Alzheimer's Disease as one in which genetics plays a role.
"And we think that this methodology can very much be used to capture the bunch of genes that are playing an important role in one's susceptibility to that disease," he said. "And the same can be true, perhaps, for looking at adult-onset diabetes 11, or cardiovascular disease, or stroke. Again, where I think there is at least a moderate impact from genetic variation."
As the cost of the needed genetic tests continues to decline, he predicts doctors will be able to screen patients for diseases they may not develop until later in life, and recommend ways to avoid them.
- A single gene may have many effects.单一基因可能具有很多种效应。
- The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
- It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
- Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
- The rabbit is a relatively recent introduction in Australia.兔子是相对较新引入澳大利亚的物种。
- The operation was relatively painless.手术相对来说不痛。
- Good habits promote longevity.良好的习惯能增长寿命。
- Human longevity runs in families.人类的长寿具有家族遗传性。
- He showed the price fluctuations in a statistical table.他用统计表显示价格的波动。
- They're making detailed statistical analysis.他们正在做具体的统计分析。
- Analyzing the date of some socialist countries presents even greater problem s. 分析某些社会主义国家的统计数据，暴露出的问题甚至更大。 来自辞典例句
- He undoubtedly was not far off the mark in analyzing its predictions. 当然，他对其预测所作的分析倒也八九不离十。 来自辞典例句
- He has a propensity for drinking too much alcohol.他有酗酒的倾向。
- She hasn't reckoned on his propensity for violence.她不曾料到他有暴力倾向。
- Only now did he understand the full complexity of the problem.直到现在他才明白这一问题的全部复杂性。
- The complexity of the road map puzzled me.错综复杂的公路图把我搞糊涂了。
- You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因，所以能够活得很长。 来自《简明英汉词典》
- Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪
- The poor children regularly pony up for a second helping of my hamburger. 那些可怜的孩子们总是要求我把我的汉堡包再给他们一份。
- By doing this, they may at times be helping to restore competition. 这样一来, 他在某些时候,有助于竞争的加强。