时间:2019-01-14 作者:英语课 分类:VOA标准英语2011年(六月)


英语课

Researchers Identify New Target in Cancer Fight


Scientists have identified a new way of fighting cancer that limits the growth and spread of a variety of tumors in laboratory animals.

When you get a cut, the area quickly becomes inflamed 2 - swollen 3, red, and tender as the body's immune system sends white blood cells to fight infection and heal the wound.

The immune system reacts to many cancers in much the same way, says University of California, San Diego researcher Judith Varner.

"The white blood cells rush to the tumor 1 and attempt to heal the 'wound' in a manner that actually never stops," she explains. "And because it doesn't stop, because the cancer doesn't go away, the white blood cells actually help the cancer to grow."

That happens when the immune system cells are 'hijacked 4' by the tumor in a way that fosters the growth and spread of tumors.

Varner and her colleagues identified a specific enzyme 5 called PI-3 kinase gamma that allows the immune cells to get into the tumor, where it can be compromised.

They figured out how to block PI-3 kinase gamma, using either drugs or genetic 6 methods, in laboratory mice.

"When we treated animals with early tumors, we found that we could stop the stage of tumor at the early stage, and we prevented the invasive stage from developing. And that's only by targeting the inflammation, even without a drug that affects the tumor cell itself," Varner says.

In addition to the mice with breast cancer, the researchers also used this approach on a variety of other cancers in laboratory animals and found it was consistently effective across a range of different kinds of tumors.

"So we were able to inhibit 7 half of all the tumor growth in pancreatic cancer, breast cancer, melanoma, lung cancer. And there's every reason to believe that any other solid tumor cancer would be also responsive."

Varner says suppressing PI-3 kinase gamma might in theory also be effective to reduce the risk of cancer in the first place, in cases where chronic 8 inflammation contributes to tumor formation.

She says human testing of PI-3 kinase gamma inhibitors to battle cancer could begin as soon as a year or so from now.

Judith Varner of the University of California, San Diego and her colleagues report on this new approach to tumors in the journal Cancer Cell.



n.(肿)瘤,肿块(英)tumour
  • He was died of a malignant tumor.他死于恶性肿瘤。
  • The surgeons irradiated the tumor.外科医生用X射线照射那个肿瘤。
adj.发炎的,红肿的v.(使)变红,发怒,过热( inflame的过去式和过去分词 )
  • His comments have inflamed teachers all over the country. 他的评论激怒了全国教师。
  • Her joints are severely inflamed. 她的关节严重发炎。 来自《简明英汉词典》
adj.肿大的,水涨的;v.使变大,肿胀
  • Her legs had got swollen from standing up all day.因为整天站着,她的双腿已经肿了。
  • A mosquito had bitten her and her arm had swollen up.蚊子叮了她,她的手臂肿起来了。
劫持( hijack的过去式和过去分词 ); 绑架; 拦路抢劫; 操纵(会议等,以推销自己的意图)
  • The plane was hijacked by two armed men on a flight from London to Rome. 飞机在从伦敦飞往罗马途中遭到两名持械男子劫持。
  • The plane was hijacked soon after it took off. 那架飞机起飞后不久被劫持了。
n.酵素,酶
  • Above a certain temperature,the enzyme molecule will become unfolded.超过一定温度,酶分子将会展开。
  • An enzyme that dissolves the fibrin of blood clots.能溶解血凝块中的纤维的酶。
adj.遗传的,遗传学的
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
vt.阻止,妨碍,抑制
  • Don't let ego and greed inhibit clear thinking and hard work.不要让自我和贪婪妨碍清晰的思维和刻苦的工作。
  • They passed a law to inhibit people from parking in the street.他们通过一项法令以阻止人们在街上停车。
adj.(疾病)长期未愈的,慢性的;极坏的
  • Famine differs from chronic malnutrition.饥荒不同于慢性营养不良。
  • Chronic poisoning may lead to death from inanition.慢性中毒也可能由虚弱导致死亡。
学英语单词
acoustic homing system
address matcher circuit
alphanumeric program
Anicetus
antirheumatoid drug
apparent turbulent stress tensor
aseptic filling
astronomic transit
atlee
automated batch mixing
Bac Giang, Tinh
bioconcentration
bistable polarization
branch coverage testing
brems
bus hut
cant rail
checking book
chrysanthemum leucanthemums
close-to-nature forestry
cobalt slass
coffee black beans
coodes
crested penguins
crystal-controlled
customer evaluation
daryosphere
diffused base transistor
distributed element
ditylenchus
externally-imposed
flower primordia
foresworn
full crystal
gateway charge
geographical classification of 8oils
guardlike
heteromorphic chromosomes
heterosperminous hybridization
histoimmunological
historical jurisprudence
horn cleat
hydroaluminations
iraqgates
knife tool
laughland
lent an ear to
liasons
limit of aperidicity
local buffer storage
lomasome
longitudinal dispersion
low transmission
mazatzal pk.
medical nomenclature
microcode assembler
mild-mannered
mine swept route
Mugila, Mts.
multispectral satellite data
noboes
obv
Osborne, L.
Paranari
patently
payment notice
Perisporiales
pick his steps
price plan
primary vaccination
protocollyris sauteri
pterygomandibular
Puusepp's reflex
raddicle
read-message
real-time data structure
recosting
reverse mottle
RNA probe
rosin adduct
scutellarin
segmented address space
spread for
sudor anglicus
Symes
symmetric game
tank clean-out opening
televisuality
the eight manifestations of infantile convulsion
theophanous
tisiyeh (tasiyeh)
torpedo bombardment aeroplane
tribenzylethyltin
trickle-irrigated
triphenoxazin
two for one twister
unquenches
versche
vica
wear resistant alloy steel
widely spaced stanchions
zapanta