时间:2018-12-08 作者:英语课 分类:VOA标准英语2015年(二月)


英语课

Generic 1 Form of Pediatric HIV Drug OK’d


A new licensing 2 agreement with the pharmaceutical 3 company MERCK allows for the manufacture of a generic version of a pediatric AIDS drug. It may be two years before it’s readily available in low- and middle-income countries. However, it’s a step toward having greater access to HIV medicines specifically designed for children.


It’s estimated there are more than three million children living with HIV, but less than a third of them received antiretroviral therapy in 2013.The U.N.-backed Medicines Patent Pool estimates 700 children are newly infected each day, while 500 die of AIDS-related causes.


The MERCK drug – raltegravir – has been approved for children as young as four weeks.


Medicines Patent Pool Executive Director Greg Perry said pediatric AIDS drugs are a neglected area of health care. As a result, many kids with HIV are forced to take adult formulations of antiretroviral pills, or ARVs.


“They will taste incorrect. They will have high alcohol content. They will be too big. The children won’t take them. So, there’s a whole series of problems with using adult formulations," he said. "And finally, worst of all, of course, is that when you try and break them down they’re not really perfectly 4 digestible to the children or working properly into the bloodstream.”


Perry explained what the licensing agreement with MERCK will do.


“It does allow really two things. It allows for generic companies to develop and then manufacture low cost versions of raltegravir. It also enables them to make improvements upon the product and, indeed, to use them in combination with other products," he said. "[This] is important because you want to see new fixed 5 dose combinations of pediatric formulations because that’s a clear need in the pediatric field.”


Currently, the drug is considered a third line of defense 6. But Perry said there are discussions about using it as a first- or second-line drug.


“It’s an important alternative to [the] current, sort of, preferred product, which is called lopinavir/ritonavir. So, from a public health point of view it’s an important product,” he said.


Perry added it’s important to have a wide variety of ARVs in the event HIV builds up resistance to current treatment. He said the Pediatric HIV Treatment Initiative aims to develop new fixed dose drug combinations. The goal is to have up to six new formulations over the next three years.


U.S. Global AIDS Coordinator 7 Dr. Deborah Birx said, “Without antiretroviral therapy 50 percent of infants with HIV die by age two and 80 percent by age five.”



1 generic
adj.一般的,普通的,共有的
  • I usually buy generic clothes instead of name brands.我通常买普通的衣服,不买名牌。
  • The generic woman appears to have an extraordinary faculty for swallowing the individual.一般妇女在婚后似乎有特别突出的抑制个性的能力。
2 licensing
v.批准,许可,颁发执照( license的现在分词 )
  • A large part of state regulation consists of occupational licensing. 大部分州的管理涉及行业的特许批准。 来自英汉非文学 - 行政法
  • That licensing procedures for projects would move faster. 这样的工程批准程序一定会加快。 来自辞典例句
3 pharmaceutical
adj.药学的,药物的;药用的,药剂师的
  • She has donated money to establish a pharmaceutical laboratory.她捐款成立了一个药剂实验室。
  • We are engaged in a legal tussle with a large pharmaceutical company.我们正同一家大制药公司闹法律纠纷。
4 perfectly
adv.完美地,无可非议地,彻底地
  • The witnesses were each perfectly certain of what they said.证人们个个对自己所说的话十分肯定。
  • Everything that we're doing is all perfectly above board.我们做的每件事情都是光明正大的。
5 fixed
adj.固定的,不变的,准备好的;(计算机)固定的
  • Have you two fixed on a date for the wedding yet?你们俩选定婚期了吗?
  • Once the aim is fixed,we should not change it arbitrarily.目标一旦确定,我们就不应该随意改变。
6 defense
n.防御,保卫;[pl.]防务工事;辩护,答辩
  • The accused has the right to defense.被告人有权获得辩护。
  • The war has impacted the area with military and defense workers.战争使那个地区挤满了军队和防御工程人员。
7 coordinator
n.协调人
  • The UN Office for the Coordination of Humanitarian Affairs, headed by the Emergency Relief Coordinator, coordinates all UN emergency relief. 联合国人道主义事务协调厅在紧急救济协调员领导下,负责协调联合国的所有紧急救济工作。
  • How am I supposed to find the client-relations coordinator? 我怎么才能找到客户关系协调员的办公室?
学英语单词
abdominal cavities
accelerator ZDMC
agrip
alginic acid
anacanthus
anti-bottom quark
arrested failure
associated emission
banderol, banderole
basic separating
basosexine
Belling saccharimeter
bepitying
Biassini
bitterweeds
cammaron
capital of Oklahoma
change-over channel steamer
charge-storage diode
chloralkaline
chlorobenzyl chloride
cholecystokinin (cck)
complemeent (darlington 1932)
correlation analysis method
countervailing
deformation loss
detectable effect
dimethyldihydroresorcinol
direct-current grid bias
distributed feedback
dyadic array
electronic shower
Elsholtzia hunanensis
filter editor
food and beverage expenses
footlongs
glass reinforced concrete glass
grant woods
harangue
heading per steering compass
herringbone pipe
hewsons
hinchleys
Holter system
incipient incision
incipient scorch
Incomati (Komati)
internal strapped block
isoolivil
laser-Raman spectrometry
laxogenin
leakage and drip
Lisfranc's tubercle
lobes
macgregor hatch cover
maximum colour acuity
medium irrigated emulsion
metachromatic bodies
Molatón
Morinville
nabzenil
negotiated meaning
nitrogen-to-protein conversion factor
non-americans
offspringless
organizatory
Otego
Over-allotment option
OWRS
Panax schin-seng Nees
Passengers Ships in Inland Waters
pastoral stage
pentetate
petersen sir elutriator
phase interchange rate
Polygonum patulum
pteroxygonum giraldii dammer et diels
rabelo
relieve stress
schwalb
scratch resistance
seat cover for vehicle
security option
seen with half an eye
self starter
sequential data structure
setting-out work
shapiro-wilk test
side by side display
superimposed preeclampsia
sweated joint
telocollinites
tendon lengthening
thermal radiation destruction distance
topological relation
total equity
ultraviolet dwarf
uredinology
Vilyuy
virtual volume
volumetrics
xanthohumol